Up to ~24%
Average body-weight reduction observed at the highest dose over 48 weeks in phase 2 research of the triple-agonist class.
Jastreboff AM, et al. Triple-Hormone-Receptor Agonist Retatrutide for Obesity — A Phase 2 Trial. NEJM, 2023.
Join 12,000+ on the protocolTransform your body
Transform your body
without the clinic
The first triple-agonist peptide protocol — pharmaceutical-grade, guided by licensed clinicians, and shipped to your door.
Pharmaceutical-grade
Compounded in licensed US pharmacies
Clinician-guided
Reviewed by licensed providers
Direct to you
No waiting rooms, no middlemen
Held to pharmaceutical standards
Pharmaceutical-grade
cGMP-manufactured
Third-party tested
purity verified
Cold-chain shipped
to your door
Clinician-reviewed
every request
The science
A new class of metabolic medicine
Triple-agonist peptides engage three hormonal pathways at once. The published research on this class is among the most promising in metabolic health.
3 receptors
GLP-1, GIP and glucagon are engaged together — addressing appetite, insulin response and energy expenditure in one molecule.
Coskun T, et al. LY3437943, a novel triple GIP/GLP-1/glucagon receptor agonist. Cell Metabolism, 2022.
Weekly
A single weekly subcutaneous dose — designed to fit real life, not a clinic schedule.
Rosenstock J, et al. Retatrutide in type 2 diabetes: phase 2 trial. The Lancet, 2023.
Glucagon
Adding glucagon-receptor activity may increase energy expenditure beyond appetite suppression alone.
Müller TD, et al. Glucagon-based therapeutics. Nature Reviews Drug Discovery, 2022.
What members are working toward
Metabolic health
Support healthier blood-sugar response and insulin sensitivity over time.
Sustainable weight
Reduce appetite and cravings so progress compounds week over week.
Energy & focus
Many members report steadier energy as their metabolism rebalances.
Confidence
Visible, measurable change you can feel — without a clinic schedule.
Longevity markers
Better weight and glucose control are linked to long-term health.
Everyday simplicity
One weekly dose, clear instructions, and a team a message away.
The glow-up
Life-changing transformations
Research consistently shows the wide-ranging benefits of sustained weight reduction — for your body, your health, and your everyday life.
- [i]Carry less weight, every day
- [ii]Steadier energy from morning to night
- [iii]Healthier blood sugar and metabolic markers
- [iv]More confidence in how you look and feel
- [v]Lower long-term health risks
Why it matters
Studies show your looks influence almost everything, from your career to your romantic life.
Higher salary
Attractive people earn 10-15% more
Hamermesh, D.S., and J. E. Biddle. (1994). The American Economic Review.
Easier job interviews
Attractive job applicants are perceived as more qualified
Puleo, R. (2006). Journal of Undergraduate Psychological Research.
Bigger tips
Attractive servers receive $1261 more in tips annually
Parrett, M. (2015). Journal of Economic Psychology.
More sales
Customers are 55% more likely to buy from attractive sales people
Reingen, P. H., & Kernan, J. B. (1993). Journal of Consumer Psychology.
A better way
A new way to get the protocol
Modern metabolic care shouldn't mean clinics, waiting rooms, and middleman markups. We took everything out of the way.
The old way
- Step 1Book a clinic visit
- Step 2Wait & repeat your story
- Step 3Pay middleman markups
- Step 4Chase refills
- Step 5Guess at dosing
The Reta1 way
- Step 1Start online
- Step 2Remote clinician review
- Step 3Direct, transparent pricing
- Step 4Auto-shipped, cold-chain
- Step 5Guided titration & support
The protocol
One molecule. Three pathways.
A triple-agonist engages the GLP-1, GIP and glucagon receptors together — addressing appetite, insulin response and energy expenditure in a single weekly dose.
01
GLP-1
Appetite & fullness
Slows gastric emptying and signals satiety, so you eat less without willpower battles.
02
GIP
Insulin response
Improves how your body handles glucose and may ease the side-effect burden of GLP-1 alone.
03
Glucagon
Energy expenditure
Adds a metabolic lever that can increase the calories you burn at rest.
Everything you need, in one box
No prescriptions to chase, no supplies to source. Your complete protocol arrives ready to start.
Your peptide protocol
Pharmaceutical-grade, cGMP-manufactured, and third-party tested for purity before it ships.
Everything to dose
Pre-measured supplies, fine-gauge needles, and alcohol swabs — nothing else to buy.
A titration schedule
A clear, conservative ramp so your body adjusts gently, week by week.
Cold-chain packaging
Temperature-controlled shipping keeps your protocol stable from our lab to your fridge.
Step-by-step guide
Plain-language instructions and short videos for confident, correct self-administration.
Direct care access
Message our clinical team any time with questions about your protocol or progress.
Built around you
Taking into account your…
Reta1 is never one-size-fits-all. Your protocol is shaped by your body, your goals, and how you respond — reviewed by a clinician at every step.
Your starting point
Weight, history, and bloodwork shape a conservative plan.
Your goals
Weight loss, metabolic health, or maintenance — we tailor it.
Your tolerance
Titration adjusts to how your body responds, week by week.
Your lifestyle
A weekly cadence built around real life, not a clinic.
Personalised planGet your personalised
Get your personalised
Reta1 plan
Understand how your body responds and start a protocol designed for your goals — clinician-reviewed and adjusted as you progress.
- 01Get your complete metabolic baseline
- 02See your projected weight-reduction trajectory
- 03Get your personalised titration protocol
- 04Track your progress and see real change
How it works
How it works. No clinic visits needed
From request to doorstep in three simple steps — clinician-reviewed, shipped cold, supported the whole way.
- 01
Share your goals
Tell us about your health history, goals, and lifestyle in a short, private intake.
- 02
Clinician review
A licensed clinician reviews your request to confirm Reta1 is a safe, appropriate fit.
- 03
Shipped to your door
Your pharmaceutical-grade protocol ships cold-chain with everything you need to start.
Clinical review
Built and reviewed by practising clinicians
Reta1 is built and reviewed by licensed clinicians and scientists. Every protocol request is reviewed by a qualified clinician before anything ships.
Dr. Helena Marsh, MD
Endocrinology · Metabolic Medicine
Board-certified endocrinologist focused on obesity medicine and incretin-based therapies.
Dr. Julian Okafor, MD
Internal Medicine
Internist specializing in cardiometabolic risk and long-term protocol management.
Dr. Priya Nair, PharmD
Clinical Pharmacology
Pharmacist overseeing sourcing, titration safety, and drug-interaction review.
Dr. Samuel Reed, PhD
Peptide Chemistry
Leads purity standards, third-party testing, and certificate-of-analysis review.
Dr. Clara Bennett, MD
Obesity Medicine
Diplomate of the American Board of Obesity Medicine; member experience and outcomes.
Dr. Idris Haddad, MD
Preventive Medicine
Designs conservative, evidence-led protocols centered on long-term safety.
The communityJoin 12,000+ people
Join 12,000+ people
on the protocol.
I'd put off treatment for years because of the clinic runaround. Reta1 made it simple — one weekly dose, clear instructions, and a team that actually answers.
The cravings just quieted down. For the first time food isn't running my day, and the weight is coming off steadily instead of all at once.
What sold me was the transparency. I could see the certificate of analysis for my batch. It felt pharmaceutical, not gray-market.
No waiting rooms, no middlemen markups. It showed up cold-packed with everything I needed. The titration plan made starting painless.
Pricing
Direct pricing. No middlemen.
What a clinic-and-pharmacy path can cost in fees and markups, Reta1 delivers at a transparent, flat rate. Pause or cancel anytime.
Monthly
1 month
$150per month
A single cycle to begin — clinician-reviewed, fully supported, no long-term commitment.
- One complete monthly protocol kit
- Clinician review of your intake
- Conservative titration schedule
- Cold-chain shipping included
- Direct messaging with the care team
Most popular
Every 3 months
3 months
$130per month, billed quarterly
Our recommended plan — lower monthly cost with a three-month commitment.
- Three months shipped together
- Ongoing clinician oversight
- Adaptive titration as you progress
- Priority cold-chain shipping
- Unlimited care-team messaging
- Pause or cancel anytime
Every 6 months
6 months
$100per month, billed every 6 months
For members committed to the long game — our lowest monthly rate, fewer deliveries.
- Six months shipped together
- Ongoing clinician oversight
- Adaptive titration as you progress
- Priority cold-chain shipping
- Unlimited care-team messaging
- Best per-month price
- No clinic markups or middleman fees
- Secure, encrypted payment processing
- Your health data is private & never sold
- Pause or cancel anytime
Is this right for me?Serious medicine,
Serious medicine,
handled with care.
Peptide therapy is powerful — and that means it deserves real oversight. Here’s how we keep Reta1 safe, honest, and human.
A clinician reviews every request
Reta1 isn't right for everyone. A licensed clinician reviews your intake and confirms eligibility before anything ships.
Conservative, transparent dosing
We start low and titrate slowly to minimize side effects. You'll always know exactly what you're taking and why.
Support that doesn't disappear
Our care team is one message away throughout your protocol. Big change is easier when you're never doing it alone.
Your questions
Frequently asked questions
Can’t find what you’re looking for? Email us at hello@reta.health.
Start my plan
Start your protocol, shipped to your door.
Join the 12,000+ people on their Reta1 protocol. Start your plan, complete a short clinician-reviewed intake, and we’ll take it from there.